Bextra:

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About Bextra
Bextra Side Effects
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FDA Warning
Stevens Johnson Syndrome
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Bextra Side Effects

Common Bextra Side Effects

Side effects of using Bextra may include, stomach pain, diarrhea, heartburn (dyspepsia), nausea, back pain, headache, and upper respiratory infection. These symptoms can range from mild to moderate. However, more severe reactions have also been reported -- some requiring hospitalization.

Bextra and Gastro-Intestinal Toxicity

Serious GI toxicity can occur without any warning symptoms with of non-steroidal anti-inflammatory medications (NSAIDs). In patients with a history of GI problems, such as ulcers, or bleeding, NSAIDs should be used with extreme caution, especially in elderly patients.

Bextra and Stevens-Johnson Syndrome

Stevens-Johnson Syndrome is a rare, severe, and sometimes fatal form of auto-immune disease. Symptoms include lesions in the mouth and eyes, headache, fever, fatigue, and conjunctivitis. Antibiotics, anticonvulsants, and nonsteroidal anti-inflammatory medications (NSAIDs) including medications such as Arava, Bextra, Vioxx, and Celebrex are often associated with Stevens-Johnson.

Bextra and Other Serious Skin Reactions

Serious skin reactions have been reported in patients treated with Bextra. These include:
- Toxic Epidermal Necrolysis, a potentially fatal skin disorder characterized by the blistering and peeling of the top layer of skin.
- Erythema Multiforme, an acute eruption of the skin called an iris or target lesion which can be mild or severe.
- Generalized Exfoliative Dermatitis, a severe inflammation of the entire skin surface

Bextra and Anaphylaxis

Anaphylaxis is a severe and potentially fatal systemic allergic reaction. Such serious allergic reactions to medications cause the most allergy-associated deaths in the United States every year.

Anaphylactic symptoms can occur within minutes, and include itching, hives, throat swelling, asthma, irregular heart rhythm, nausea, vomiting, abdominal cramps, and a loss of consciousness.

People who have experienced asthma or allergic reactions after taking aspirin or NSAIDs should not take Bextra. They may experience a severe anaphylactic-like reactions to Bextra.
Bextra also should not be taken by patients who have demonstrated allergic-type reactions to sulfonamides. Since the FDA's warning in November 2002, Pharmacia has been warning doctors not to give Bextra to patients who were allergic to sulfa drugs. However, you or a loved one may have taken Bextra before this -- or your doctor may have failed to ask you about sulfonamides.


Bextra Side Effects

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