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Celebrex Side Effects
Common Celebrex Side Effects
The most common side effects in clinical trials were indigestion,
diarrhea, and abdominal pain, upper respiratory tract infections,
and nausea. These symptoms can range from mild to moderate.
However, more severe reactions have also been reported --
some requiring hospitalization.
Celebrex and Gastro-Intestinal Toxicity
Serious GI toxicity can occur without any warning symptoms
with of non-steroidal anti-inflammatory medications (NSAIDs).
In patients with a history of GI problems, such as ulcers,
or bleeding, NSAIDs should be used with extreme caution, especially
in elderly patients.
Celebrex and other NSAID medicines can cause stomach ulcers
that bleed. The chance of this serious problem increases the
longer you take Celebrex and with higher doses of Celebrex.
Stomach bleeding can also happen suddenly while you take Celebrex.
Celebrex and Stevens-Johnson Syndrome
Stevens-Johnson Syndrome is a rare, severe, and sometimes
fatal form of auto-immune disease. Symptoms include lesions
in the mouth and eyes, headache, fever, fatigue, and conjunctivitis.
Antibiotics, anticonvulsants, and nonsteroidal anti-inflammatory
medications (NSAIDs) including medications such as Arava,
Celebrex, Vioxx,
and Bextra, are often associated
with Stevens-Johnson
Syndrome.
Celebrex and Anaphylaxis
Anaphylaxis is a severe and potentially fatal systemic allergic
reaction. Such serious allergic reactions to medications cause
the most allergy-associated deaths in the United States every
year
Anaphylactic symptoms can occur within minutes, and include
itching, hives, throat swelling, asthma, irregular heart rhythm,
nausea, vomiting, abdominal cramps, and a loss of consciousness.
Celebrex also should not be taken by patients who have demonstrated
allergic-type reactions to sulfonamides. However, you or a
loved one may have taken Celebrex before this -- or your doctor
may have failed to ask you about sulfonamides.
If you have asthma, you may have aspirin-sensitive asthma.
If an aspirin-sensitive asthmatic takes aspirin it can cause
severe narrowing of the airway (bronchospasm), and even death.
Since this type of reaction to aspirin and other NSAID medicines
have happened in aspirin-sensitive patients, aspirin-sensitive
patients should not take Celebrex.
Celebrex and Kidney Problems
Celebrex and other NSAID medicines can cause serious problems
such as liver damage. Some of the warning signs of liver damage
are nausea, vomiting, tiredness, loss of appetite, itching,
yellow coloring of skin or eyes, "flu-like" symptoms
and dark urine. If these happen, stop taking Celebrex and
call your health care provider right away.
Celebrex and other NSAID medicines can cause serious kidney
problems that include sudden kidney failure or worsening of
kidney problems that you already have.
Celebrex Side Effects
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