Permax:

Permax
Permax Side Effects
Parkinson's Disease
Heart Valve Disease
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Permax Side Effects

Permax

Permax (pergolide mesylate) has been on the market since 1989. Permax was developed by Eli Lilly and is now manufactured and marketed by Amarin Corporation in San Francisco. Since Permax was approved for treatment of Parkinson's disease patients, more than 500,000 people have taken the drug.

Permax is referred to as a dopamine agonist, which describes the way in which it works inside the body. Dopamine agonists are a promising category of drugs used to treat disease. Permax is most commonly used in the treatment of the early stages of Parkinson's disease, and is especially effective in patients not previously treated for the disease. People whose legs jump, itch, tingle or feel otherwise restless at night - and for some, throughout the day - may also get relief from pergolide.

Permax Side Effects

Permax side effects include:

  • nervous system complaints, including involuntary spasms, sleepiness, hallucinations, dizziness, and insomnia
  • digestive complaints, including nausea, constipation, diarrhea, and indigestion
  • respiratory system complaints, such as a runny nose

The FDA has contacted Eli Lilly about the latest reports of heart valve disease. It has recommended that the company change the labeling of pergolide to add information about occurrences of valvular heart disease in the warnings section of the label.


Permax Side Effects

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